“Itching caused by touch becomes more common as we age and is especially problematic for people with dry skin or who already suffer from chronic itching,” said senior investigator Hongzhen Hu, PhD, an associate professor of anesthesiology who conducts research as part of the university’s Center for the Study of Itch. The fewer the receptors, the more likely it is that touching will induce itching. Their research, published May 4 in the journal Science, indicates that itching caused by touch is directly related to the number of touch receptors embedded in the skin. Now, researchers at Washington University School of Medicine in St Louis have discovered, in mice, why a touch can cause such severe itching and, in the process, identified some possible therapeutic targets. What’s worse, anti-itch treatments, including hydrocortisone, don’t provide much relief for this type of itching. For some people, particularly those who are elderly, even a light touch of the skin or contact with clothing can lead to unbearable itching.
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